<div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Forma farmacéutica</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Comprimido oral</span></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Composición por dosis</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline; color: rgb(0, 0, 0);">Firocoxib 57 mg; óxido de hierro (E172); caramelo (E150d).</span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Propiedades farmacológicas</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline; color: rgb(0, 0, 0);">El firocoxib es un antiinflamatorio no esteroideo (AINE) perteneciente al grupo de coxibes, que actúa por inhibición selectiva de la ciclooxigenasa-2 (COX-2), mediadora de la síntesis de prostaglandinas. COX-2 es la isoforma del enzima que ha sido postulado como responsable principal de la síntesis de prostanoides mediadores del dolor, de la inflamación y de la fiebre. En ensayos realizados in vitro en sangre de perro entera, el firocoxib mostró una selectividad para COX-2 aproximadamente 380 veces más que para COX-1.</span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Interacciones e incompatibilidades</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="color: rgb(0, 0, 0);"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Un tratamiento previo con otros antiinflamatorios puede provocar la aparición o la agravación de efectos adversos y por lo tanto se recomienda mantener un periodo de al menos 24 horas sin ningún tratamiento antes de empezar el tratamiento con Previcox 57 mg. La duración de este periodo de transición debe, no obstante, ser adaptada en función de las propiedades farmacocinéticas de los productos utilizados anteriormente.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 10pt; vertical-align: baseline;"><span style="font-family: Raleway; font-size: 14px;"> No administrar Previcox</span><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: 0; font-family: Raleway; font-size: 14px; vertical-align: baseline; position: relative; top: -0.5em;">®</span><span style="font-family: Raleway; font-size: 14px;"> simultáneamente con otros AINE o con glucocorticoides. Una ulceración del tracto gastrointestinal puede ser exacerbada por los corticoides en animales a los que se administran antiinflamatorios no esteroideos.</span></span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> El tratamiento simultáneo con moléculas que muestren una acción sobre el flujo renal, como por ejemplo diuréticos o inhibidores de la enzima de conversión de la angiotensina (ECA), debe estar sujeto a control clínico. Debe evitarse la administración simultánea de sustancias activas potencialmente nefrotóxicas ya que puede haber un aumento del riesgo de toxicidad renal.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Cualquier otra sustancia activa que presente un alto grado de enlace a proteínas, puede competir para enlazarse con éstas, si se usa simultaneamente con firocoxib y puede por ello provocar efectos tóxicos.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Debido a que los medicamentos anestésicos pueden afectar la perfusión renal, deberá considerarse la posibilidad de utilizar una terapia con fluídos vía parenteral durante la intervención, a fin de disminuir las potenciales complicaciones renales cuando se utilizan AINE durante el periodo perioperatorio.</span></span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Indicaciones y especies de destino</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><div style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 10pt; vertical-align: baseline;"><strong style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 13.3333px; vertical-align: baseline;"><span style="font-family: Raleway; font-size: 14px;">Perros</span></strong><span style="font-family: Raleway; font-size: 14px;">: Alivio del dolor y de la inflamación asociadas a la osteoartritis en el perro; alivio del dolor posoperatorio y la inflamación asociados a la cirugía de tejido blando, dental y ortopédico.</span></span></div></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Contraindicaciones</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="color: rgb(0, 0, 0);"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> No usar durante la gestación y la lactancia.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> No utilizar en animales de menos de 10 semanas de edad o de menos de 3 kg de peso.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> No utilizar en animales que padezcan hemorragia gastrointestinal, discrasia sanguínea o trastornos hemorrágicos.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> No utilizar simultáneamente con corticosteroides o con otros antiinflamatorios no esteroideos (AINE).</span></span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Efectos secundarios</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="color: rgb(0, 0, 0);"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Ocasionalmente han sido observados emesis y diarrea. Estas reacciones son generalmente transitorias y reversibles cuando se para el tratamiento. En muy raras ocasiones, se han notificado casos de trastornos hepáticos y/o renales en perros a los que se les había administrado la dosis de tratamiento recomendada. En raras ocasiones, se han notificado casos de trastornos del sistema nervioso en perros tratados.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Se define la frecuencia de las posibles reacciones adversas usando el convenio siguiente:</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Rara (afecta entre 1 y 10 animales por cada 10000).</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Muy rara (afecta a menos de 1 animal por cada 10000).</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Si aparecieran reacciones adversas como vómitos, diarrea repetida, sangre fecal oculta, pérdida súbita de peso, anorexia, letargia, degradación de los parámetros bioquímicos renales o hepáticos, el uso del producto debería ser suspendido y se debería pedir consejo a un veterinario. Como sucede con otros AINE, pueden producirse reacciones adversas graves que, en muy raras ocasiones, pueden ser mortales.</span></span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Vía de administración</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline; color: rgb(0, 0, 0);">Oral.</span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Posología</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="color: rgb(0, 0, 0);"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 10pt; vertical-align: baseline;"><strong style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 13.3333px; vertical-align: baseline;"><span style="font-family: Raleway; font-size: 14px;">Perros:</span></strong><span style="font-family: Raleway; font-size: 14px;"> 5 mg/kg una vez al día.</span></span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Administrar por vía oral según la tabla siguiente:</span></span></p><table cellspacing="0" border="0" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; border-spacing: 0px; max-width: 100%; background-color: transparent; width: 438px; height: 190px;"><tbody style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td rowspan="2" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"><strong style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 13.3333px; vertical-align: baseline;">Peso corporal (kg)</strong></span></td><td colspan="2" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"><strong style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 13.3333px; vertical-align: baseline;">Número de comprimidos masticables por presentación</strong></span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"><strong style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 13.3333px; vertical-align: baseline;">57 mg</strong></span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"><strong style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 13.3333px; vertical-align: baseline;">227 mg</strong></span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">3-5,5</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">0,5</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">5,6-10</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">1</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">10,1-15</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">1,5</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">15,1-22</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">0,5</span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">22,1-45</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">1</span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">45,1-68</span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td><td align="center" style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">1,5</span></td></tr><tr style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline;"><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">68,1-90</span></td><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> </span></td><td style="margin: 0px; padding: 9px 10px; border: 1px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: middle; text-align: center;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">2</span></td></tr></tbody></table><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="color: rgb(0, 0, 0);"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Los comprimidos pueden ser administrados o no con el alimento. No exceder la dosis recomendada.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> La duración del tratamiento dependerá de la respuesta observada. Como los estudios de campo estuvieron limitados a 90 días, un tratamiento de larga duración debe ser examinado con cuidado y bajo supervisión veterinaria regular.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; font-size: 10pt; vertical-align: baseline;"><span style="font-family: Raleway; font-size: 14px;"> Los comprimidos masticables Previcox</span><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: 0; font-family: Raleway; font-size: 14px; vertical-align: baseline; position: relative; top: -0.5em;">®</span><span style="font-family: Raleway; font-size: 14px;"> 57 mg son divisibles a fin de asegurar una dosificación precisa y contienen aromas ahumado y caramelo a fin de facilitar su administración en el perro.</span></span></span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;">Precauciones especiales</span></div><div class="producto_texto" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><p style="margin-bottom: 1em; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: inherit; vertical-align: baseline; min-height: 1px;"><span style="color: rgb(0, 0, 0);"><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> El uso en animales muy jóvenes o en animales con sospecha o confirmación de insuficiencia renal, cardiaca o hepática puede conllevar un riesgo adicional. Si en este caso no se puede evitar el uso, estos perros requerirán un cuidadoso control veterinario.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Úsese este producto bajo estricto control veterinario cuando haya un riesgo de hemorragia gastrointestinal, o si el animal ha mostrado anteriormente intolerancia a los AINE. En muy raras ocasiones, se han notificado casos de trastornos hepáticos y/o renales en perros a los que se había administrado la dosis de tratamiento recomendada. Es posible que una proporción de estos perros padeciera enfermedad hepática o renal subclínica antes del inicio de la terapia. Por lo tanto, se recomienda realizar una prueba de laboratorio adecuada antes y periódicamente durante la administración para establecer los parámetros bioquímicos hepáticos o los parámetros basales renales.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Evitar el uso en animales deshidratados, hipovolémicos o hipotensos, ya que hay un riesgo de aumento de la toxicidad renal. Debe evitarse la administración simultánea de sustancias activas parcialmente nefrotóxicas.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Estudios de laboratorio en conejos han puesto de manifiesto efectos maternotóxicos o fetotóxicos a dosis que se aproximan a la dosis de tratamiento recomendada para el perro.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> En caso de ingestión accidental, consulte inmediatamente con un médico y muéstrele el prospecto o la etiqueta.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Lávese las manos después de usar el producto.</span><br><span style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; font-family: Raleway; font-size: 14px; vertical-align: baseline;"> Todo medicamento no utilizado o los residuos derivados del mismo deberán eliminarse de conformidad con las normativas locales.</span></span></p></div><div class="producto_apartado" style="margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; line-height: inherit; vertical-align: baseline; text-align: justify;"><span style="font-family: Raleway; font-size: 14px;"> Importante:</span><strong style="font-family: inherit; font-style: inherit; font-variant: inherit; margin: 0px; padding: 0px; border: 0px; font-stretch: inherit; line-height: inherit; font-size: 13.3333px; vertical-align: baseline;"><span style="font-family: Raleway; font-size: 14px;"> Venta bajo Receta Medico veterinaria.</span></strong><br></div>
